Light Chain Disease

Light chain deposition disease lcdd is a rare condition characterized by the deposition of specific proteins monoclonal light chains in the kidneys and other organs light chains are used to make antibodies that the body needs to fight infection.

Light chain disease. Your body fights infection with antibodies. Certain cells in your body called b cells often make extra light chains that are broken down into small pieces by the kidney which are then reabsorbed and used again continued. The kidneys are almost always affected and this often leads to kidney failure. Light chain deposition disease lcdd is the most common form of ig deposition disease and has been considered as a contraindication to transplant.

It is a rare disease characterized by deposition of nonamyloid immunoglobulin light chains and they do not stain with congo red and do not exhibit a fibrillar structure when examined ultrastructurally. Light chain deposition disease lcdd is the deposition of monoclonal light chains in multiple organs. Light chain deposition disease lcdd is a rare blood cell disease which is characterized by deposition of fragments of infection fighting immunoglobulins called light chains lcs in the body. Light chain deposition disease lcdd is the deposition of monoclonal light chains in multiple organs.

What is light chain deposition disease. It is a rare disease characterized by deposition of nonamyloid immunoglobulin light chains which do not stain with congo red and do not exhibit a fibrillar structure when examined ultrastructurally. People with lcdd make too many light chains which get deposited in many body tissues while lcdd can occur in any organ the kidneys are always.